Cancer genomics

Mathematical models for tumour sequencing data: purity and copy number, cancer cell fractions, mutation detection power, mutational signatures and the timing of genomic events.

• GISTIC permutation null for copy-number scores
• Molecular timing of copy-number gains
• Mutational signatures and Bayesian NMF
• Tumour purity, ploidy and copy-ratio algebra
• Detection power for somatic mutations
• Cancer cell fraction estimation
• Saturation power for cancer gene discovery

The dependency explorer needs JavaScript and its graph data.

Download the complete graph data.